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ESOPEC: prospective randomized controlled multicenter phase III trial comparing perioperative chemotherapy (FLOT protocol) to neoadjuvant chemoradiation (CROSS protocol) in patients with adenocarcinoma of the esophagus (NCT02509286)
BMC Cancer · 2016 · Vol. 16(1) · pp. 503–503
Jens Hoeppner✉(University of Freiburg)Florian LordickThomas Brunner(University Medical Center Freiburg)Torben Glatz(University of Freiburg)Peter Bronsert(University of Freiburg)Nadine Röthling(University Medical Center Freiburg)Claudia Schmoor(University Medical Center Freiburg)Dietmar Lorenz(Sana Klinikum Offenbach)Christian Ell(Sana Klinikum Offenbach)Ulrich T. Hopt(University of Freiburg)J. R. Siewert(University Medical Center Freiburg)
Abstract
NCT02509286 (July 22, 2015).
Esophageal Cancer Research and TreatmentGastric Cancer Management and OutcomesMetastasis and carcinoma case studiesMedicineSurgical oncologyPerioperativeEsophageal adenocarcinomaProtocol (science)Randomized controlled trialOncologyChemotherapyAdenocarcinomaInternal medicine
MeSH terms
AdenocarcinomaAdultAgedAntineoplastic Combined Chemotherapy ProtocolsDrug TherapyEsophageal NeoplasmsEsophagusFemaleHumansMaleMiddle AgedNeoplasm Recurrence, LocalProspective StudiesQuality of LifeRadiotherapy
Funding
- Deutsche Forschungsgemeinschaft
- Army Research Office
Citations
344
FWCI
21.03
field-weighted impact
References
22
Percentile
100%
vs. same field & year
Citations per year
References
A phase II study
European Journal of Cancer · 2000 · 752 citations
Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal carcinoma: an updated meta-analysis
The Lancet Oncology · 2011 · 1,648 citations
Perioperative Chemotherapy versus Surgery Alone for Resectable Gastroesophageal Cancer
New England Journal of Medicine · 2006 · 6,297 citations
Perioperative Chemotherapy Compared With Surgery Alone for Resectable Gastroesophageal Adenocarcinoma: An FNCLCC and FFCD Multicenter Phase III Trial
Journal of Clinical Oncology · 2011 · 2,078 citations
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