review Open AccessTop 1% cited
Platelet Activation: The Mechanisms and Potential Biomarkers
BioMed Research International · 2016 · Vol. 2016 · pp. 1–5
Seong-Hoon Yun(Dong-A University)Eun-Hye Sim(Dong-A University)Ri-Young Goh(Dong-A University)Joo‐In Park(Dong-A University)Jin‐Yeong Han✉(Dong-A University)
Abstract
Beyond hemostasis and thrombosis, an increasing number of studies indicate that platelets play an integral role in intercellular communication, mediating inflammatory and immunomodulatory activities. Our knowledge about how platelets modulate inflammatory and immunity has greatly improved in recent years. In this review, we discuss recent advances in the pathways of platelet activation and potential application of platelet activation biomarkers to diagnosis and prediction of disease states.
Platelet Disorders and TreatmentsAntiplatelet Therapy and Cardiovascular DiseasesVenous Thromboembolism Diagnosis and ManagementPlatelet activationPlateletHemostasisThrombosisMedicineImmunologyInflammationImmunityDiseaseBioinformatics
MeSH terms
AnimalsBlood PlateletsHumansInflammationBiomarkersPlatelet ActivationImmunomodulation
Funding
- National Research Foundation
- Ministry of Science, ICT and Future Planning
- National Research Foundation of Korea
Citations
498
FWCI
21.61
field-weighted impact
References
30
Percentile
100%
vs. same field & year
Citations per year
References
Mechanisms of platelet activation: Need for new strategies to protect against platelet-mediated atherothrombosis
Thrombosis and Haemostasis · 2009 · 432 citations
The role of platelets in inflammation
Thrombosis and Haemostasis · 2015 · 520 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.