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Effectiveness and safety of oral HIV preexposure prophylaxis for all populations

AIDS · 2016 · Vol. 30(12) · pp. 1973–1983

Abstract

PrEP is protective against HIV infection across populations, presents few significant safety risks, and there is no evidence of behavioral risk compensation. The effective and cost-effective use of PrEP will require development of best practices for fostering uptake and adherence among people at substantial HIV risk.

HIV/AIDS Research and InterventionsHIV, Drug Use, Sexual RiskAdolescent Sexual and Reproductive HealthPre-exposure prophylaxisMedicineAdverse effectMeta-analysisPlaceboRisk compensationRelative riskConfidence intervalInternal medicineHuman immunodeficiency virus (HIV)

MeSH terms

TenofovirAdministration, OralAdultFemaleHumansMalePlacebosHIV InfectionsChemopreventionAnti-HIV AgentsYoung AdultPre-Exposure Prophylaxis

Funding

  • Bill and Melinda Gates Foundation
Citations
1,008
FWCI
66.02
field-weighted impact
References
55
Percentile
100%
vs. same field & year
Citations per year
Cited by
Mental health and HIV/AIDS
AIDS · 2019 · 701 citations
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