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Binding Characteristics of a Radiolabeled Agonist and Antagonist at Central Nervous System Alpha Noradrenergic Receptors
Molecular Pharmacology · 1977 · Vol. 13(3) · pp. 454–473
David C. U’Prichard✉(Johns Hopkins University)David A. Greenberg(Johns Hopkins University)Solomon H. Snyder(Johns Hopkins University)
Plant and fungal interactionsChemical synthesis and alkaloidsAdvanced Synthetic Organic ChemistryAgonistPartial agonistChemistryAntagonistClonidineReceptorBinding siteNorepinephrineStereochemistryInternal medicine
MeSH terms
Adrenergic alpha-AgonistsAdrenergic alpha-AntagonistsAnimalsBinding SitesBinding, CompetitiveBrainClonidineDioxanesDioxinsErgot AlkaloidsHydroxydopaminesKineticsMaleNorepinephrinePhenethylamines
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Clonidine binds to imidazole binding sites as well as α2-adrenoceptors in the ventrolateral medulla
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