articleTop 1% cited

Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese.

Molecular Pharmacology · 1994 · Vol. 46(4) · pp. 594–598

Sara Moráis✉(National Institute of Environmental Health Sciences)G. Wilkinson(National Institute of Environmental Health Sciences)Joyce Blaisdell(National Institute of Environmental Health Sciences)Urs Meyer(National Institute of Environmental Health Sciences)Kōichi Nakamura(National Institute of Environmental Health Sciences)Jorge Goldstein(National Institute of Environmental Health Sciences)

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Pharmacogenetics and Drug Metabolism Diet and metabolism studies Metabolism and Genetic DisordersGeneticsMephenytoinAlleleBiologyGenotypingCYP2C19GenotypePharmacogeneticsGene

MeSH terms

Amino Acid SequenceAryl Hydrocarbon HydroxylasesBase SequenceCytochrome P-450 Enzyme SystemFemaleHeterozygoteHomozygoteHumansMixed Function OxygenasesJapanMaleMephenytoinMolecular Sequence DataPedigreePolymorphism, Genetic

Citations

750

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18.82

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