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Hydrogels with tunable stress relaxation regulate stem cell fate and activity

Nature Materials · 2015 · Vol. 15(3) · pp. 326–334
Ovijit ChaudhuriLuo GuDarinka D. KlumpersMax DarnellSidi A. BencherifJames C. WeaverNathaniel HuebschHong-Pyo LeeEvi LippensGeorg N. DudaDavid Mooney
Cellular Mechanics and Interactions3D Printing in Biomedical ResearchBone Tissue Engineering MaterialsSelf-healing hydrogelsStress relaxationExtracellular matrixAdhesionCell adhesionMesenchymal stem cellBiophysicsMaterials scienceViscoelasticityElastic modulus

MeSH terms

AlginatesBiomechanical PhenomenaCell DifferentiationExtracellular MatrixHexuronic AcidsHumansStress, MechanicalCell Culture TechniquesHydrogelsGlucuronic AcidMesenchymal Stem Cells

Funding

  • ZonMw
  • Einstein Stiftung Berlin
  • Berlin-Brandenburger Centrum für Regenerative Therapien
  • Berlin-Brandenburg School for Regenerative Therapies
  • National Institutes of Health
  • Materials Research Science and Engineering Center, Harvard University
  • Division of Materials Research
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