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Immune-related adverse events with immune checkpoint blockade: a comprehensive review

European Journal of Cancer · 2016 · Vol. 54 · pp. 139–148

Jean‐Marie Michot✉(Institut Gustave Roussy)Camille Bigenwald(Institut Gustave Roussy)Stéphane Champiat(Institut Gustave Roussy)Michael Collins(Université Paris-Sud)Franck Carbonnel(Université Paris-Sud)Sophie Postel‐Vinay(Institut Gustave Roussy)A. Berdelou(Institut Gustave Roussy)Andreea Varga(Institut Gustave Roussy)Rastislav Bahleda(Institut Gustave Roussy)Antoine Hollebecque(Institut Gustave Roussy)Christophe Massard(Institut Gustave Roussy)Alina Fuerea(Institut Gustave Roussy)Vincent Ribrag(Institut Gustave Roussy)Anas Gazzah(Institut Gustave Roussy)Jean‐Pierre Armand(Institut Gustave Roussy)Nadia Amellal(Institut Gustave Roussy)Eric Angevin(Institut Gustave Roussy)Nicolas Noël(Université Paris-Sud)C. Boutros(Institut Gustave Roussy)Christine Mateus(Institut Gustave Roussy)Caroline Robert(Institut Gustave Roussy)Jean‐Charles Soria(Institut Gustave Roussy)Aurélien Marabelle(Institut Gustave Roussy)Olivier Lambotte(Université Paris-Sud)

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Cancer Immunotherapy and Biomarkers Immune Cell Function and Interaction Cancer, Stress, Anesthesia, and Immune ResponseImmune systemMedicineImmunotherapyAdverse effectImmunologyImmunosuppressionIpilimumabImmune checkpointCancerCytotoxic T cell

MeSH terms

AbataceptAnimalsAntibodiesAntineoplastic AgentsHumansImmunotherapyNeoplasmsRisk FactorsSignal TransductionTreatment OutcomeMolecular Targeted TherapyB7-H1 AntigenCTLA-4 AntigenDrug-Related Side Effects and Adverse Reactions

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Neurological adverse events associated with immune checkpoint inhibitors: Review of the literature