review Open AccessTop 1% cited

Accuracy of non-invasive prenatal testing using cell-free DNA for detection of Down, Edwards and Patau syndromes: a systematic review and meta-analysis

BMJ Open · 2016 · Vol. 6(1) · pp. e010002–e010002

Sian Taylor‐Phillips(University of Warwick)Karoline Freeman(University of Warwick)Julia Geppert(University of Warwick)Adeola Agbebiyi(University of Warwick)Olalekan A. Uthman(University of Warwick)Jason Madan(University of Warwick)Angus Clarke(Cardiff University)Siobhan Quenby(University of Warwick)Aileen Clarke✉(University of Warwick)

View via DOI Full-text PDF

Abstract

CRD42014014947.

Prenatal Screening and Diagnostics Parvovirus B19 Infection Studies Fetal and Pediatric Neurological DisordersMedicineMeta-analysisCell-free fetal DNAPrenatal diagnosisPregnancyPathologyGeneticsFetus

MeSH terms

Trisomy 13 SyndromeTrisomy 18 SyndromeChromosomes, Human, Pair 13Chromosomes, Human, Pair 18DNADown SyndromeFemaleHumansPregnancyPrenatal DiagnosisSensitivity and SpecificityTrisomyBiomarkersChromosome Disorders