Physico-chemical and phytochemical standardization of Itrifal Ustukhuddus: a pharmacopoeial Unani compound formulation.

Abstract

Physico-chemical standardization is an important part in quality control of Unani drugs both single as well as compound formulation as the therapeutic efficacy of the drugs mainly depends upon their chemical constituents. Therefore, the determination of physico-chemical characters for the authenticity of a drug is necessary before studying it for pharmacological activity. In the present study a pharmacopoeial compound formulation Itrifal Ustukhuddus has been selected to confirm its parameter according to the guidelines given in Unani Pharmacopoeia of India. The parameters studied for quality assurance of Itrifal Ustukhuddus includes physicochemical studies and qualitative analysis of various phytochemicals was estimated that revealed the presence of carbohydrates, glycosides, phenols, proteins, steroids and resins. The TLC profile of this formulation was also performed. This study will help in setting down pharmacopoeial standards in determining the quality and purity of compound drug formulation which is in use since time immemorial in chronic catarrh, sinusitis, as a Nervine tonic.