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Titanium surface characteristics, including topography and wettability, alter macrophage activation

Acta Biomaterialia · 2015 · Vol. 31 · pp. 425–434
Kelly HotchkissGireesh B. ReddySharon L. HyzyZvi SchwartzBarbara D. BoyanRené Olivares‐Navarrete
Bone Tissue Engineering MaterialsOrthopaedic implants and arthroplastyGraphene and Nanomaterials ApplicationsBiomaterialMaterials scienceWettingBiocompatibilityContact angleMacrophageTitaniumBiophysicsCytokineBiomedical engineering

MeSH terms

Anti-Inflammatory AgentsBiocompatible MaterialsCell DifferentiationHumansInflammationMacrophage ActivationMacrophagesOsteoblastsOsteogenesisPolystyrenesSurface PropertiesTitaniumTumor Necrosis Factor-alphaInterleukin-6Osseointegration

Funding

  • International Association for Dental Research
  • Academy of Osseointegration
  • National Institutes of Health
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases
Citations
650
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References
Macrophage plasticity and polarization in tissue repair and remodelling
The Journal of Pathology · 2012 · 2,323 citations
Environmental sensing through focal adhesions
Nature Reviews Molecular Cell Biology · 2008 · 2,484 citations
Monocyte and macrophage heterogeneity
Nature reviews. Immunology · 2005 · 5,112 citations
Exploring the full spectrum of macrophage activation
Nature reviews. Immunology · 2008 · 8,962 citations
Macrophage plasticity and polarization: in vivo veritas
Journal of Clinical Investigation · 2012 · 6,260 citations
Macrophage phenotypes during tissue repair
Journal of Leukocyte Biology · 2013 · 635 citations
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