article Open AccessTop 1% cited

Adjuvant Whole-Brain Radiotherapy Versus Observation After Radiosurgery or Surgical Resection of One to Three Cerebral Metastases: Results of the EORTC 22952-26001 Study

Journal of Clinical Oncology · 2010 · Vol. 29(2) · pp. 134–141

Martin Köcher✉(University of Turin)Riccardo Soffietti(University of Turin)Ufuk Abacıoğlu(University of Turin)S. Villà(University of Turin)F. Fauchon(University of Turin)Brigitta G. Baumert(University of Turin)Laura Fariselli(University of Turin)Tzahala Tzuk-Shina(University of Turin)Rolf‐Dieter Kortmann(University of Turin)C. Carrié(University of Turin)Mohamed Ben Hassel(University of Turin)Mauri Kouri(University of Turin)Egils Valeinis(University of Turin)D. Van Den Berge(University of Turin)Sandra Collette(University of Turin)Laurence Collette(University of Turin)Rolf‐Peter Mueller(University of Turin)

View via DOI Full-text PDF

Abstract

After radiosurgery or surgery of a limited number of brain metastases, adjuvant WBRT reduces intracranial relapses and neurologic deaths but fails to improve the duration of functional independence and overall survival.

Brain Metastases and Treatment Lung Cancer Research Studies Glioma Diagnosis and TreatmentMedicineRadiosurgeryClinical endpointRadiation therapyAdjuvantSurgeryBrain metastasisLung cancerCancerRandomized controlled trial

MeSH terms

AdultAgedAged, 80 and overBrain NeoplasmsFemaleHumansMaleMiddle AgedRadiotherapySurvival RateRadiosurgerySalvage TherapyDisease ProgressionDisease-Free SurvivalRadiotherapy, Adjuvant

Citations

1,982

FWCI

70.95

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

Cited by

Metastatic non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up