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The effect of combined antiretroviral therapy on the overall mortality of HIV-infected individuals
AIDS · 2009 · Vol. 24(1) · pp. 123–137
The HIV-CAUSAL Collaboration✉(Harvard University)
Abstract
We estimated that cART halved the average mortality rate in HIV-infected individuals. The mortality reduction was greater in those with worse prognosis at the start of follow-up.
HIV/AIDS Research and InterventionsHIV Research and TreatmentHIV/AIDS drug development and treatmentCartMarginal structural modelHazard ratioConfoundingMedicineConfidence intervalAntiretroviral therapyInternal medicineProportional hazards modelProspective cohort study
MeSH terms
AdultDrug Administration ScheduleDrug Therapy, CombinationEuropeFemaleHumansMaleMiddle AgedTime FactorsUnited StatesHIV-1HIV InfectionsProportional Hazards ModelsCD4 Lymphocyte CountViral Load
Citations
469
FWCI
11.29
field-weighted impact
References
39
Percentile
99%
vs. same field & year
Citations per year
Cited by
Prevention of HIV-1 Infection with Early Antiretroviral Therapy
New England Journal of Medicine · 2011 · 6,930 citations
References
1993 Revised Classification System for HIV Infection and Expanded Surveillance Case Definition for AIDS Among Adolescents and Adults
Clinical Infectious Diseases · 1993 · 4,360 citations
Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection
PLoS Medicine · 2008 · 1,595 citations
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