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Sleep-Disordered Breathing and Mortality: A Prospective Cohort Study

PLoS Medicine · 2009 · Vol. 6(8) · pp. e1000132–e1000132
Naresh M. PunjabiBrian CaffoJames L. GoodwinDaniel J. GottliebAnne B. NewmanGeorge O'connorDavid M. RapoportSusan RedlineHelaine E. ResnickJohn A. RobbinsEyal ShaharMark L. UnruhJonathan M. Samet

Abstract

Sleep-disordered breathing is associated with all-cause mortality and specifically that due to coronary artery disease, particularly in men aged 40-70 y with severe sleep-disordered breathing. Please see later in the article for the Editors' Summary.

Obstructive Sleep Apnea ResearchNeuroscience of respiration and sleepCardiovascular and Diving-Related ComplicationsMedicineHazard ratioSleep apneaBody mass indexInternal medicineProportional hazards modelPolysomnographySleep studyObstructive sleep apneaCohort

MeSH terms

AgedHypoxiaCoronary Artery DiseaseFemaleHumansMaleMiddle AgedProspective StudiesRisk FactorsSex FactorsSleep Apnea SyndromesProportional Hazards ModelsOdds RatioSurvival Analysis

Funding

  • University of Minnesota
  • University of Washington
  • Johns Hopkins University
  • Case Western Reserve University
  • Sleep Research Society
  • ResMed
  • York University
  • University of California, Davis
  • National Heart, Lung, and Blood Institute
Citations
1,446
FWCI
42.18
field-weighted impact
References
37
Percentile
100%
vs. same field & year
Citations per year
References
Mortality and Apnea Index in Obstructive Sleep Apnea
CHEST Journal · 1988 · 1,513 citations
Epidemiology of Obstructive Sleep Apnea: A Population Health Perspective
American Journal of Respiratory and Critical Care Medicine · 2002 · 4,206 citations
Sleep-disordered Breathing and Cardiovascular Disease
American Journal of Respiratory and Critical Care Medicine · 2001 · 2,900 citations
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