review Open AccessTop 1% cited
Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence
Cochrane Database of Systematic Reviews · 2009 · pp. CD002209–CD002209
Richard P. Mattick✉(UNSW Sydney)Courtney Breen(National Centre for Clinical Research on Emerging Drugs)Jo Kimber(London School of Hygiene & Tropical Medicine)Marina Davoli(Azienda Sanitaria Locale Roma 3)
Abstract
Methadone is an effective maintenance therapy intervention for the treatment of heroin dependence as it retains patients in treatment and decreases heroin use better than treatments that do not utilise opioid replacement therapy. It does not show a statistically significant superior effect on criminal activity or mortality.
Opioid Use Disorder TreatmentSubstance Abuse Treatment and OutcomesTreatment of Major DepressionMethadoneMethadone maintenanceMedicineOpioidPlaceboRandomized controlled trialHeroinCochrane LibraryPsychiatryAlcohol dependence
MeSH terms
HumansInactivation, MetabolicMethadoneOpioid-Related DisordersNarcoticsRandomized Controlled Trials as Topic
Citations
1,611
FWCI
77.21
field-weighted impact
References
34
Percentile
100%
vs. same field & year
Citations per year
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