article Open Access
Hypocortisolism in survivors of severe acute respiratory syndrome (SARS)
Clinical Endocrinology · 2005 · Vol. 63(2) · pp. 197–202
Melvin Khee‐Shing Leow✉(Tan Tock Seng Hospital)Daniel Seow‐Khee Kwek(Tan Tock Seng Hospital)Alan Wei‐Keong Ng(Tan Tock Seng Hospital)Kian‐Chung Ong(Tan Tock Seng Hospital)Gregory Jon‐Leng Kaw(Tan Tock Seng Hospital)Lawrence Lee(National Centre for Infectious Diseases)
Abstract
These preliminary findings highlight a possible aetiologic role of SARS-associated coronavirus in causing a reversible hypophysitis or direct hypothalamic effect, with the HPA axis affected more frequently than the HPT axis.
Stress Responses and CortisolLong-Term Effects of COVID-19Thyroid Disorders and TreatmentsSubclinical infectionEndocrine systemMedicinePediatricsConcomitantInternal medicineCohortHormoneEndocrinology
MeSH terms
Adrenocorticotropic HormoneAdultAnti-Inflammatory AgentsFemaleHumansHydrocortisoneHypothalamo-Hypophyseal SystemMaleMethylprednisoloneMiddle AgedPituitary-Adrenal SystemPrednisoloneProspective StudiesThyroid DiseasesSevere Acute Respiratory Syndrome
Funding
- Agency for Science, Technology and Research
- Biomedical Research Council
Citations
296
FWCI
0.48
field-weighted impact
References
30
Percentile
55%
vs. same field & year
Citations per year
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Clinical Microbiology Reviews · 2007 · 1,224 citations
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