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Hypocortisolism in survivors of severe acute respiratory syndrome (SARS)

Clinical Endocrinology · 2005 · Vol. 63(2) · pp. 197–202
Melvin Khee‐Shing LeowDaniel Seow‐Khee KwekAlan Wei‐Keong NgKian‐Chung OngGregory Jon‐Leng KawLawrence Lee

Abstract

These preliminary findings highlight a possible aetiologic role of SARS-associated coronavirus in causing a reversible hypophysitis or direct hypothalamic effect, with the HPA axis affected more frequently than the HPT axis.

Stress Responses and CortisolLong-Term Effects of COVID-19Thyroid Disorders and TreatmentsSubclinical infectionEndocrine systemMedicinePediatricsConcomitantInternal medicineCohortHormoneEndocrinology

MeSH terms

Adrenocorticotropic HormoneAdultAnti-Inflammatory AgentsFemaleHumansHydrocortisoneHypothalamo-Hypophyseal SystemMaleMethylprednisoloneMiddle AgedPituitary-Adrenal SystemPrednisoloneProspective StudiesThyroid DiseasesSevere Acute Respiratory Syndrome

Funding

  • Agency for Science, Technology and Research
  • Biomedical Research Council
Citations
296
FWCI
0.48
field-weighted impact
References
30
Percentile
55%
vs. same field & year
Citations per year
Cited by
Thyrotoxicosis in patients with COVID-19: the THYRCOV study
European Journal of Endocrinology · 2020 · 359 citations
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