articleTop 1% cited
Time course EPI of human brain function during task activation
Magnetic Resonance in Medicine · 1992 · Vol. 25(2) · pp. 390–397
Peter A. Bandettini✉(Medical College of Wisconsin)Eric C. Wong(Medical College of Wisconsin)R. Scott Hinks(Applied Sciences Laboratory (United States))Ronald S. Tikofsky(Medical College of Wisconsin)James S. Hyde(Medical College of Wisconsin)
Abstract
Using gradient-echo echo-planar MRI, a local signal increase of 4.3 +/- 0.3% is observed in the human brain during task activation, suggesting a local decrease in blood deoxyhemoglobin concentration and an increase in blood oxygenation. Images highlighting areas of signal enhancement temporally correlated to the task are created.
Advanced MRI Techniques and ApplicationsAdvanced Neuroimaging Techniques and ApplicationsNMR spectroscopy and applicationsBlood oxygenationHuman brainSIGNAL (programming language)Task (project management)Echo (communications protocol)OxygenationGradient echoBrain functionNeuroscienceNuclear magnetic resonance
MeSH terms
BrainHemoglobinsHumansMagnetic Resonance ImagingOxygenPartial PressureTask Performance and Analysis
Funding
- National Institutes of Health
Citations
1,940
FWCI
51.97
field-weighted impact
References
21
Percentile
100%
vs. same field & year
Citations per year
Cited by
The Brain's Default Mode Network
Annual Review of Neuroscience · 2015 · 3,970 citations
Functional analysis of human MT and related visual cortical areas using magnetic resonance imaging
Journal of Neuroscience · 1995 · 1,441 citations
Analysis of functional MRI time‐series
Human Brain Mapping · 1994 · 1,710 citations
A Model for the Coupling between Cerebral Blood Flow and Oxygen Metabolism during Neural Stimulation
Journal of Cerebral Blood Flow & Metabolism · 1997 · 817 citations
Mechanisms of Visual Attention in the Human Cortex
Annual Review of Neuroscience · 2000 · 2,181 citations
The neural basis of the blood–oxygen–level–dependent functional magnetic resonance imaging signal
Philosophical Transactions of the Royal Society B Biological Sciences · 2002 · 948 citations
A Functional MRI Study of Subjects Recovered From Hemiparetic Stroke
Stroke · 1997 · 1,029 citations
BRAIN WORK AND BRAIN IMAGING
Annual Review of Neuroscience · 2006 · 1,643 citations
References
Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field
Biochimica et Biophysica Acta (BBA) - General Subjects · 1982 · 1,132 citations
Dynamic imaging with lanthanide chelates in normal brain: Contrast due to magnetic susceptibility effects
Magnetic Resonance in Medicine · 1988 · 706 citations
Oxygenation‐sensitive contrast in magnetic resonance image of rodent brain at high magnetic fields
Magnetic Resonance in Medicine · 1990 · 2,258 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.