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Contemporary predictors of death and sustained ventricular tachycardia in patients with repaired tetralogy of Fallot enrolled in the INDICATOR cohort

Heart · 2013 · Vol. 100(3) · pp. 247–253

Anne Marie Valente✉(Boston Children's Hospital)Kimberlee Gauvreau(Boston Children's Hospital)Gabriele Egidy Assenza(Boston Children's Hospital)Sonya V. Babu‐Narayan(Royal Brompton & Harefield NHS Foundation Trust)Jenna Schreier(Imperial College London)Michael Α. Gatzoulis(Royal Brompton & Harefield NHS Foundation Trust)Maarten Groenink(Academic Medical Center)Ryo Inuzuka(Academic Medical Center)Philip J. Kilner(Imperial College London)Zeliha Koyak(Academic Medical Center)Michael J. Landzberg(Harvard University)Barbara J.M. Mulder(Academic Medical Center)Andrew J. Powell(Boston Children's Hospital)Rachel M. Wald(Harvard University)Tal Geva(Harvard University)

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Abstract

RV hypertrophy, ventricular dysfunction and atrial tachyarrhythmias are predictive of death and sustained VT in adults with repaired TOF. These findings may inform risk stratification and the design of future therapeutic trials.

Congenital Heart Disease Studies Cardiac Arrhythmias and Treatments Coronary Artery AnomaliesMedicineInternal medicineCardiologyTetralogy of FallotVentricular tachycardiaCohortProportional hazards modelLeft ventricular hypertrophyHeart diseaseBlood pressure

MeSH terms

AdolescentAdultAgedCanadaChildChild, PreschoolElectrocardiographyEuropeExercise TestHumansInfantMagnetic Resonance ImagingMiddle AgedPredictive Value of TestsPrognosis