review Open AccessTop 1% cited

The incretin system and its role in type 2 diabetes mellitus

Molecular and Cellular Endocrinology · 2008 · Vol. 297(1-2) · pp. 127–136

Jens J. Holst✉(University of Copenhagen)T. Vilsboll(University of Copenhagen)Carolyn F. Deacon(University of Copenhagen)

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Diabetes Treatment and Management Metabolism, Diabetes, and Cancer Pancreatic function and diabetesIncretinInternal medicineEndocrinologyHormoneGastric inhibitory polypeptidePostprandialMedicineDiabetes mellitusType 2 diabetesInsulin

MeSH terms

Glucagon-Like Peptide-1 ReceptorAnimalsDiabetes Mellitus, Type 2HumansReceptors, GlucagonGlucagon-Like Peptide 1IncretinsDipeptidyl-Peptidase IV Inhibitors

Citations

509

FWCI

18.85

field-weighted impact

References

122

Percentile

100%

vs. same field & year

Citations per year

References

Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 1999 · 526 citations

Exendin-4 reduces fasting and postprandial glucose and decreases energy intake in healthy volunteers

American Journal of Physiology-Endocrinology and Metabolism · 2001 · 467 citations

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus.

Journal of Clinical Investigation · 1993 · 1,635 citations

Glucagon‐like peptide‐1 decreases endogenous amyloid‐β peptide (Aβ) levels and protects hippocampal neurons from death induced by Aβ and iron

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Molecular and Cellular Endocrinology

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Peptide hormone exendin‐4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of parkinson's disease

Journal of Neuroscience Research · 2007 · 340 citations

The biology of incretin hormones

Cell Metabolism · 2006 · 2,140 citations

Reduced incretin effect in Type 2 (non-insulin-dependent) diabetes

Diabetologia · 1986 · 1,298 citations

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus.

Journal of Clinical Investigation · 1993 · 1,635 citations

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