articleTop 10% cited
Clinical manifestation and prognostic factor in anti-melanoma differentiation-associated gene 5 antibody-associated interstitial lung disease as a complication of dermatomyositis
Lara D. Veeken · 2010 · Vol. 49(9) · pp. 1713–1719
Takahisa Gono✉(Tokyo Women's Medical University)Yoshiharu KawaguchiTetsuo SatohMasataka KuwanaYasuhiro KatsumataKae TakagiIkuko MasudaA. TochimotoS. BabaYuko OkamotoYuko OtaHisashi Yamanaka
Abstract
Both serum ferritin and anti-MDA5 antibody are powerful indicators for the early diagnosis of A/SIP with DM. Ferritin also predicts disease severity and prognosis for patients with anti-MDA5 antibody. Intensive treatment should be administered to cases that have anti-MDA5 antibody-associated ILD with DM showing hyperferritinaemia, especially if the ferritin level is >or=1600 ng/ml.
Inflammatory Myopathies and DermatomyositisInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisEosinophilic Disorders and SyndromesMedicineDermatomyositisInterstitial lung diseaseMDA5MelanomaComplicationAntibodyDiseasePathologyLung
MeSH terms
Interferon-Induced Helicase, IFIH1AdultAutoantibodiesDermatomyositisFemaleFerritinsHumansMacrophage ActivationMaleMiddle AgedPrognosisRetrospective StudiesStatistics as TopicBiomarkersLung Diseases, Interstitial
Citations
324
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6.26
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References
34
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97%
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Cited by
Anti-MDA5 antibody, ferritin and IL-18 are useful for the evaluation of response to treatment in interstitial lung disease with anti-MDA5 antibody-positive dermatomyositis
Lara D. Veeken · 2012 · 330 citations
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References
Idiopathic Pulmonary Fibrosis: Diagnosis and Treatment: International Consensus Statement
American Journal of Respiratory and Critical Care Medicine · 2000 · 2,622 citations
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