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An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity

European Journal of Pharmacology · 1998 · Vol. 353(1) · pp. 23–31
Shimon Ben‐ShabatEster FrideTzviel SheskinTsippy TamiriMan Hee RheeZvi VogelTiziana BisognoLuciano De PetrocellisVincenzo Di MarzoRaphael Mechoulam
Cannabis and Cannabinoid ResearchGABA and Rice ResearchNeuroscience of respiration and sleepCannabinoid receptorCannabinoidGlycerolAdenylyl cyclaseEndogenyChemistryEndocannabinoid systemBiochemistryReceptorAnandamide

MeSH terms

Adenylyl Cyclase InhibitorsAnalgesicsAnimalsArachidonic AcidsCannabinoidsCell LineDrug SynergismEnzyme InhibitorsFemaleGlyceridesHydrolysisHypothermiaLigandsGas Chromatography-Mass SpectrometryMotor Activity

Funding

  • Hebrew University of Jerusalem
  • Israel Science Foundation
  • National Institute on Drug Abuse
Citations
613
FWCI
10.43
field-weighted impact
References
22
Percentile
99%
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Citations per year
Cited by
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References
Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs
Pharmacology Biochemistry and Behavior · 1991 · 406 citations
2-Arachidonoylgylcerol: A Possible Endogenous Cannabinoid Receptor Ligand in Brain
Biochemical and Biophysical Research Communications · 1995 · 2,177 citations
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