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Association of nutritional status and serum albumin levels with development of toxicity in patients with advanced non-small cell lung cancer treated with paclitaxel-cisplatin chemotherapy: a prospective study

BMC Cancer · 2010 · Vol. 10(1) · pp. 50–50

Óscar Arrieta✉(Instituto Nacional de Cancerología)Rosa M. Michel Ortega(Instituto Nacional de Cancerología)Geraldine Villanueva-Rodríguez(Instituto Nacional de Cancerología)M.G. Serna-Thomé(Instituto Nacional de Cancerología)Diana Flores‐Estrada(Instituto Nacional de Cancerología)Consuelo Díaz-Romero(Instituto Nacional de Cancerología)Cindy M Rodríguez(Instituto Nacional de Cancerología)Luis A. Martinez(Instituto Nacional de Enfermedades Respiratorias)Karla Sánchez-Lara(Hospital Médica Sur)

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Abstract

SIR parameters were associated with malnutrition, weight loss and hypoalbuminemia. Chemotherapy-induced toxicity in NSCLC patients treated with paclitaxel and cisplatin was associated with malnutrition and hypoalbuminemia. Early nutritional assessment and support might confer beneficial effects.

Inflammatory Biomarkers in Disease Prognosis Acute Myeloid Leukemia Research Cancer survivorship and careHypoalbuminemiaMedicineInternal medicineLeukopeniaGastroenterologyToxicityChemotherapyLung cancerAlbuminAnemia

MeSH terms

AgedAntineoplastic Combined Chemotherapy ProtocolsCarcinoma, Non-Small-Cell LungCisplatinFemaleHumansLung NeoplasmsLymphocytesMaleMiddle AgedNutritional StatusProspective StudiesSerum AlbuminPaclitaxelMalnutrition