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A SINGLE IMMEDIATE POSTOPERATIVE INSTILLATION OF CHEMOTHERAPY DECREASES THE RISK OF RECURRENCE IN PATIENTS WITH STAGE Ta T1 BLADDER CANCER: A META-ANALYSIS OF PUBLISHED RESULTS OF RANDOMIZED CLINICAL TRIALS

The Journal of Urology · 2004 · Vol. 171(6 Part 1) · pp. 2186–2190

Richard Sylvester✉Willem OosterlinckAdrian P.M. van der Meijden

Abstract

One immediate intravesical instillation of chemotherapy significantly decreases the risk of recurrence after TUR in patients with stage Ta T1 single and multiple bladder cancer. It is the treatment of choice in patients with a single, low risk papillary tumor and is recommended as the initial treatment after TUR in patients with higher risk tumors.

Bladder and Urothelial Cancer Treatments Multiple and Secondary Primary Cancers Glutathione Transferases and PolymorphismsMedicineStage (stratigraphy)Bladder cancerRandomized controlled trialChemotherapyMeta-analysisOncologyCancerUrothelial cancerCancer recurrence

MeSH terms

Administration, IntravesicalAntineoplastic AgentsUrinary Bladder NeoplasmsCombined Modality TherapyHumansNeoplasm Recurrence, LocalNeoplasm StagingPostoperative CareRisk FactorsTime FactorsRandomized Controlled Trials as Topic

Citations

737

FWCI

29.48

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

Cited by

A retrospective & prospective study to know that en-bloc TURBT for non-muscle invasive bladder carcinoma better than conventional TURBT in terms of tumor recurrence and tumor progression in South Indian