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Muscle Strength and Body Mass Index as Long-Term Predictors of Mortality in Initially Healthy Men

The Journals of Gerontology Series A · 2000 · Vol. 55(3) · pp. M168–M173

Taina Rantanen✉(National Institute on Aging)T. B. Harris✉(National Institute on Aging)Suzanne G. Leveille✉(National Institutes of Health)Marjolein Visser✉(Vrije Universiteit Amsterdam)Daniel J. Foley✉(National Institute on Aging)Kamal Masaki✉(Kuakini Medical Center)J. M. Guralnik✉(National Institutes of Health)

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Abstract

In healthy middle-aged men, long-term mortality risk was associated with grip strength at baseline, independent of BMI. The possible interpretation of the finding is that early life influences on muscle strength may have long-term implications for mortality. Additionally, higher strength itself may provide greater physiologic and functional reserve that protects against mortality.

Nutrition and Health in Aging Body Composition Measurement Techniques Obesity, Physical Activity, DietGrip strengthBody mass indexMedicineHand strengthConfidence intervalDemographyMortality rateInternal medicineProportional hazards modelPhysical therapy

MeSH terms

AgedAgingHumansMaleMiddle AgedMortalityMuscle ContractionPredictive Value of TestsProspective StudiesReference ValuesBody Mass IndexProportional Hazards ModelsMuscle, SkeletalHand Strength

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Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women