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Trends in mortality in patients with systemic sclerosis over 40 years: a systematic review and meta-analysis of cohort studies

Lara D. Veeken · 2011 · Vol. 51(6) · pp. 1017–1026
Muriel ElhaïChristophe MeuneJérôme AvouacAlan S. KahanY. Allanore

Abstract

Our results confirm that SSc is a devastating condition as reflected by a pooled SMR of 3.5. Additionally, SMR has not significantly changed over the past 40 years. Further studies are needed to assess the effect of the most recent available therapies on mortality in SSc.

Systemic Sclerosis and Related DiseasesMast cells and histamineRenal Diseases and GlomerulopathiesMedicineMeta-analysisCohortCohort studyInternal medicineMeta-regressionStandardized mortality ratioMortality rate

MeSH terms

HumansMortalityRisk FactorsScleroderma, SystemicCohort Studies
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