article Open AccessTop 1% cited
Time to Initiation of Fluconazole Therapy Impacts Mortality in Patients with Candidemia: A Multi‐Institutional Study
Clinical Infectious Diseases · 2006 · Vol. 43(1) · pp. 25–31
Kevin W. Garey✉(University of Houston)M Rege(University of Houston)Manjunath P. Pai(University of New Mexico)Dana E. Mingo(Baptist Memorial Health Care)Katie J. Suda(University of Tennessee Health Science Center)Robin S. Turpin(United States Military Academy)David T. Bearden(Oregon State University)
Abstract
A delay in the initiation of fluconazole therapy in hospitalized patients with candidemia significantly impacted mortality. New methods to avoid delays in appropriate antifungal therapy, such as rapid diagnostic tests or identification of unique risk factors, are needed.
Antifungal resistance and susceptibilityFungal Infections and StudiesAntibiotic Use and ResistanceFluconazoleMedicineFungemiaInternal medicineCandida glabrataCandida tropicalisCandida parapsilosisCandida albicansRetrospective cohort studyMycosis
MeSH terms
AdultAgedAntifungal AgentsCandidiasisFemaleHumansLength of StayMaleMiddle AgedRetrospective StudiesTime FactorsCohort StudiesFluconazoleFungemia
Funding
- Enzon Pharmaceuticals
- University of Houston
Citations
1,154
FWCI
25.46
field-weighted impact
References
20
Percentile
100%
vs. same field & year
Citations per year
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References
Attributable Mortality of Nosocomial Candidemia, Revisited
Clinical Infectious Diseases · 2003 · 1,137 citations
The Influence of Inadequate Antimicrobial Treatment of Bloodstream Infections on Patient Outcomes in the ICU Setting
CHEST Journal · 2000 · 1,794 citations
Delaying the Empiric Treatment of <i>Candida</i> Bloodstream Infection until Positive Blood Culture Results Are Obtained: a Potential Risk Factor for Hospital Mortality
Antimicrobial Agents and Chemotherapy · 2005 · 1,268 citations
Nosocomial Bloodstream Infections in US Hospitals: Analysis of 24,179 Cases from a Prospective Nationwide Surveillance Study
Clinical Infectious Diseases · 2004 · 4,487 citations
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