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SAMPLING VARIANCES OF HETEROZYGOSITY AND GENETIC DISTANCE
Genetics · 1974 · Vol. 76(2) · pp. 379–390
Masatoshi Nei✉(The University of Texas Health Science Center at Houston)A. K. Roychoudhury(The University of Texas Health Science Center at Houston)
Abstract
Mathematical formulae for the sampling variances of average heterozygosity and Nei's genetic distance are developed. These sampling variances are decomposed into their two components, i.e. the inter-locus and intra-locus variances. The relationship between the number of loci and the number of individuals per locus to be examined for estimating average heterozygosity and genetic distance is also discussed. The utility of the inter-locus variance of heterozygosity for studying the mechanism of maintenance of genetic variability in populations is indicated.
Genetic diversity and population structureGenetic Mapping and Diversity in Plants and AnimalsChromosomal and Genetic VariationsLoss of heterozygosityLocus (genetics)BiologyGeneticsStatisticsGenetic distanceSampling (signal processing)Genetic variationEvolutionary biologyAllele
MeSH terms
AllelesAnimalsChromosome MappingGene FrequencyGenetics, PopulationHeterozygoteHumansMathematics
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References
Genetic Distance between Populations
The American Naturalist · 1972 · 9,820 citations
PHYLOGENETIC ANALYSIS: MODELS AND ESTIMATION PROCEDURES
Evolution · 1967 · 2,236 citations
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