article Open AccessTop 1% cited
Hypnotics' association with mortality or cancer: a matched cohort study
BMJ Open · 2012 · Vol. 2(1) · pp. e000850–e000850
Daniel F. Kripke✉(Scripps Clinic)Robert D. Langer(Jackson Memorial Hospital)Lawrence E. Kline(Scripps Clinic)
Abstract
Receiving hypnotic prescriptions was associated with greater than threefold increased hazards of death even when prescribed <18 pills/year. This association held in separate analyses for several commonly used hypnotics and for newer shorter-acting drugs. Control of selective prescription of hypnotics for patients in poor health did not explain the observed excess mortality.
Sleep and related disordersDiet and metabolism studiesChildhood Cancer Survivors' Quality of LifeMedicineEpidemiologyCohort studyCohortCancerAssociation (psychology)Internal medicineFamily medicineOncology
Funding
- University of California, San Diego
Citations
398
FWCI
45.51
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References
39
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100%
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References
Mortality Associated With Sleep Duration and Insomnia
Archives of General Psychiatry · 2002 · 1,616 citations
Risk Factors for Falls among Elderly Persons Living in the Community
New England Journal of Medicine · 1988 · 6,520 citations
The global health burden of infection‐associated cancers in the year 2002
International Journal of Cancer · 2006 · 2,920 citations
Excess mortality in depression: a meta-analysis of community studies
Journal of Affective Disorders · 2002 · 801 citations
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