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Adverse Childhood Experiences and Adult Risk Factors for Age-Related Disease
Archives of Pediatrics and Adolescent Medicine · 2009 · Vol. 163(12) · pp. 1135–43
Andrea Danese✉Terrie E. MoffittHonaLee Harrington(Duke University)Barry Milne(King's College London)Guilherme V. Polanczyk(Duke University)Carmine M. ParianteRichie Poulton(University of Otago)Avshalom Caspi
Abstract
Children exposed to adverse psychosocial experiences have enduring emotional, immune, and metabolic abnormalities that contribute to explaining their elevated risk for age-related disease. The promotion of healthy psychosocial experiences for children is a necessary and potentially cost-effective target for the prevention of age-related disease.
Birth, Development, and HealthStress Responses and CortisolHealth disparities and outcomesMedicineGlycated hemoglobinPsychosocialCohort studyInternal medicinePediatricsDiabetes mellitusEndocrinologyType 2 diabetesPsychiatry
MeSH terms
AdultAge FactorsChildChild AbuseCholesterolDepressionFemaleGlycated HemoglobinHumansHypertensionInflammationLife Change EventsCholesterol, HDLLongitudinal StudiesMale
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References
The metabolic syndrome
The Lancet · 2010 · 6,311 citations
Inflammation and metabolic disorders
Nature · 2006 · 8,779 citations
CORONARY DISEASE AMONG UNITED STATES SOLDIERS KILLED IN ACTION IN KOREA
Journal of the American Medical Association · 1953 · 887 citations
C-Reactive Protein, Interleukin 6, and Risk of Developing Type 2 Diabetes Mellitus
JAMA · 2001 · 4,400 citations
Socially Isolated Children 20 Years Later
Archives of Pediatrics and Adolescent Medicine · 2006 · 416 citations
Mood Disorders in the Medically Ill: Scientific Review and Recommendations
Biological Psychiatry · 2005 · 1,068 citations
The need to belong: Desire for interpersonal attachments as a fundamental human motivation.
Psychological Bulletin · 1995 · 21,114 citations
Alternative projections of mortality and disability by cause 1990–2020: Global Burden of Disease Study
The Lancet · 1997 · 7,025 citations
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