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Inhibition of Microglial Activation Attenuates the Development but Not Existing Hypersensitivity in a Rat Model of Neuropathy

Journal of Pharmacology and Experimental Therapeutics · 2003 · Vol. 306(2) · pp. 624–630
Raghavendra VasudevaFlobert TangaJoyce A. DeLeo
Pain Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration MechanismsNerve injury and regenerationHyperalgesiaMedicineAllodyniaNeuropathic painMinocyclineMicrogliaProinflammatory cytokineSpinal cordPharmacologyAnesthesia

MeSH terms

AnimalsHyperalgesiaHypersensitivityMinocyclinePainSpinal NervesGene ExpressionCytokinesRats, Sprague-DawleyMicrogliaRats
Citations
787
FWCI
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References
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References
Cellular inflammatory response after spinal cord injury in sprague-dawley and lewis rats
The Journal of Comparative Neurology · 1997 · 894 citations
Microglia: a sensor for pathological events in the CNS
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Inhibition of Microglial Activation Attenuates the Development but Not Existing Hypersensitivity in a Rat Model of Neuropathy · Scinovex