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Refining Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Using a Novel Risk Factor-Based Approach

CHEST Journal · 2009 · Vol. 137(2) · pp. 263–272

Gregory Y.H. Lip✉(University of Birmingham)Robby Nieuwlaat(Maastricht University Medical Centre)Ron Pisters(Maastricht University Medical Centre)Deirdre A. Lane(University of Birmingham)Harry J.G.M. Crijns(Maastricht University Medical Centre)

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Abstract

Our novel, simple stroke risk stratification schema, based on a risk factor approach, provides some improvement in predictive value for TE over the CHADS(2) schema, with low event rates in low-risk subjects and the classification of only a small proportion of subjects into the intermediate-risk category. This schema could improve our approach to stroke risk stratification in patients with AF.

Atrial Fibrillation Management and Outcomes Acute Ischemic Stroke Management Venous Thromboembolism Diagnosis and ManagementMedicineSchema (genetic algorithms)Framingham Risk ScoreAtrial fibrillationCohortCategorizationHeart failureInternal medicineCardiologyDisease

MeSH terms

AgedAtrial FibrillationEuropeFemaleFollow-Up StudiesHumansMalePopulation SurveillancePrognosisRetrospective StudiesRisk FactorsThromboembolismReproducibility of ResultsIncidenceRisk Assessment

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6,654

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98.13

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Stroke Risk Factors, Genetics, and Prevention