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Should patients with acute coronary disease be stratified for management according to their risk? Derivation, external validation and outcomes using the updated GRACE risk score

BMJ Open · 2014 · Vol. 4(2) · pp. e004425–e004425

Keith A.A. Fox✉(University of Edinburgh)Gordon FitzGerald(University of Massachusetts Chan Medical School)Étienne Puymirat(Hôpital Européen Georges-Pompidou)Wei Huang(University of Massachusetts Chan Medical School)Kathryn Carruthers(University of Edinburgh)Tabassome Simon(Hôpital Cardiologique du Haut-Lévêque)Pierre Coste(HIA du Val-de-Grâce à Paris)Jacques Monségu(HIA du Val-de-Grâce à Paris)Philippe Gabríel Steg(Université Paris Cité)Nicolas Danchin(Assistance Publique – Hôpitaux de Paris)Fred Anderson(University of Massachusetts Chan Medical School)

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Abstract

The updated GRACE risk score has better discrimination and is easier to use than the previous score based on linear associations. GRACE Risk (2.0) performed equally well acutely and over the longer term and can be used in a variety of clinical settings to aid management decisions.

Acute Myocardial Infarction Research Cardiac Imaging and Diagnostics Antiplatelet Therapy and Cardiovascular DiseasesMedicineFramingham Risk ScoreEpidemiologyRisk assessmentAcute coronary syndromeDiseaseRisk managementInternal medicineEmergency medicineIntensive care medicine

MeSH terms

Age FactorsAgedAlgorithmsBlood PressureCreatinineElectrocardiographyFemaleHumansMaleMiddle AgedMyocardial InfarctionPulseRisk FactorsTime FactorsModels, Statistical