article Open AccessTop 10% cited
Automated Detection and Differentiation of Drusen, Exudates, and Cotton-Wool Spots in Digital Color Fundus Photographs for Diabetic Retinopathy Diagnosis
Investigative Ophthalmology & Visual Science · 2007 · Vol. 48(5) · pp. 2260–2260
Meindert Niemeijer✉(University Medical Center Utrecht)Bram van Ginneken(University Medical Center Utrecht)Stephen R. Russell(Iowa City VA Medical Center)Maria S.A. Suttorp-Schulten(OLVG)Michael D. Abràmoff(University of Iowa)
Abstract
A machine learning-based, automated system capable of detecting exudates and cotton-wool spots and differentiating them from drusen in color images obtained in community based diabetic patients has been developed and approaches the performance level of retinal experts. If the machine learning can be improved with additional training data sets, it may be useful for detecting clinically important bright lesions, enhancing early diagnosis, and reducing visual loss in patients with diabetes.
Retinal Imaging and AnalysisRetinal Diseases and TreatmentsGlaucoma and retinal disordersCotton wool spotsDrusenDiabetic retinopathyFundus (uterus)RetinalWoolRetinopathyOphthalmologyMedicineArtificial intelligence
MeSH terms
AlgorithmsArtificial IntelligenceDiabetic RetinopathyExudates and TransudatesFundus OculiHumansImage Interpretation, Computer-AssistedPattern Recognition, AutomatedPhotographyRetinal DiseasesRetinal VesselsROC CurveSensitivity and SpecificityRetinal DrusenComputational Biology
Citations
396
FWCI
11.64
field-weighted impact
References
29
Percentile
99%
vs. same field & year
Citations per year
References
Automatic detection of diabetic retinopathy using an artificial neural network: a screening tool.
British Journal of Ophthalmology · 1996 · 505 citations
Locating blood vessels in retinal images by piecewise threshold probing of a matched filter response
IEEE Transactions on Medical Imaging · 2000 · 2,542 citations
Ridge-Based Vessel Segmentation in Color Images of the Retina
IEEE Transactions on Medical Imaging · 2004 · 4,069 citations
A contribution of image processing to the diagnosis of diabetic retinopathy-detection of exudates in color fundus images of the human retina
IEEE Transactions on Medical Imaging · 2002 · 820 citations
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