review Open AccessTop 1% cited

Effect of antibiotic prescribing in primary care on antimicrobial resistance in individual patients: systematic review and meta-analysis

BMJ · 2010 · Vol. 340(may18 2) · pp. c2096–c2096

Céire Costelloe✉(University of Bristol)Chris Metcalfe(University of Bristol)Andrew Lovering(Southmead Hospital)David Mant(Primary Health Care)Alastair D Hay(University of Bristol)

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Abstract

Individuals prescribed an antibiotic in primary care for a respiratory or urinary infection develop bacterial resistance to that antibiotic. The effect is greatest in the month immediately after treatment but may persist for up to 12 months. This effect not only increases the population carriage of organisms resistant to first line antibiotics, but also creates the conditions for increased use of second line antibiotics in the community.

Antibiotic Use and Resistance Urinary Tract Infections Management Bacterial Identification and Susceptibility TestingMedicineMeta-analysisObservational studyAntibiotic resistanceCochrane LibraryOdds ratioAntibioticsInternal medicineMEDLINEConfidence interval

MeSH terms

Anti-Bacterial AgentsDrug Resistance, MicrobialFamily PracticeHumansPractice Patterns, Physicians'Respiratory Tract InfectionsUrinary Tract Infections

Citations

1,995

FWCI

92.63

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

Cited by

Non-prescription antimicrobial use worldwide: a systematic review