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Concurrent Chemotherapy and Pelvic Radiation Therapy Compared With Pelvic Radiation Therapy Alone as Adjuvant Therapy After Radical Surgery in High-Risk Early-Stage Cancer of the Cervix

Journal of Clinical Oncology · 2000 · Vol. 18(8) · pp. 1606–1613

William A. Peters✉(Los Angeles Medical Center)P.Y. Liu(Los Angeles Medical Center)Rolland J. Barrett(Los Angeles Medical Center)Richard J. Stock(Los Angeles Medical Center)Bradley J. Monk(Los Angeles Medical Center)Jonathan S. Berek(Los Angeles Medical Center)Luís Souhami(Los Angeles Medical Center)Perry W. Grigsby(Los Angeles Medical Center)William Gordon(Los Angeles Medical Center)David S. Alberts(Los Angeles Medical Center)

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Abstract

The addition of concurrent cisplatin-based CT to RT significantly improves progression-free and overall survival for high-risk, early-stage patients who undergo radical hysterectomy and pelvic lymphadenectomy for carcinoma of the cervix.

Endometrial and Cervical Cancer Treatments Colorectal and Anal Carcinomas Ovarian cancer diagnosis and treatmentMedicineParametriumRadiation therapyCervixStage (stratigraphy)Cervical cancerChemotherapyLymphadenectomySurgeryCarcinoma

MeSH terms

AdultAgedAntineoplastic Combined Chemotherapy ProtocolsUterine Cervical NeoplasmsCisplatinCombined Modality TherapyFemaleFluorouracilHumansHysterectomyLymph Node ExcisionMiddle AgedPelvisRadiotherapy DosageSurvival Rate

Citations

2,309

FWCI

64.17

field-weighted impact

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100%

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Cited by

Validation of the 2018 FIGO cervical cancer staging system