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The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse

Developmental Cell · 2013 · Vol. 24(2) · pp. 206–214

Phillip Grote✉(Max Planck Institute for Molecular Genetics)Lars Wittler(Max Planck Institute for Molecular Genetics)David A. Hendrix(Broad Institute)Frédéric Koch(Max Planck Institute for Molecular Genetics)Sandra Währisch(Max Planck Institute for Molecular Genetics)Arica Beisaw(Max Planck Institute for Molecular Genetics)Karol Macura(Max Planck Institute for Molecular Genetics)Gaby Bläß(Max Planck Institute for Molecular Genetics)Manolis Kellis(Broad Institute)Martin Werber(Max Planck Institute for Molecular Genetics)Bernhard G. Herrmann(Max Planck Institute for Molecular Genetics)

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Cancer-related molecular mechanisms research RNA modifications and cancer RNA Research and SplicingPRC2BiologyMesodermChromatinCell biologyTranscription factorRegulatorHistoneChromatin immunoprecipitationEmbryonic stem cell

MeSH terms

Homeobox Protein PITX2AnimalsCell DifferentiationEmbryo, MammalianHeartHistonesMolecular Sequence DataPromoter Regions, GeneticHistone-Lysine N-MethyltransferaseTranscription FactorsHomeodomain ProteinsDNA MethylationEmbryonic DevelopmentMiceMyeloid-Lymphoid Leukemia Protein

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Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches