article Open AccessTop 1% cited
Use of cryo-banked oocytes in an ovum donation programme: a prospective, randomized, controlled, clinical trial
Human Reproduction · 2010 · Vol. 25(9) · pp. 2239–2246
A. Cobo✉(Valencian Infertility Institute)Marcos Meseguer(Universitat de València)J. Remohı́(Valencian Infertility Institute)António Pellicer(Universitat de València)
Abstract
This controlled-randomized, clinical trial confirmed the effectiveness of oocyte cryo-storage in an ovum donation programme, failing to demonstrate the superiority of using fresh oocytes with respect to the use of vitrified egg-banked ones in terms of OPR. Instead, the non-inferiority of vitrified oocytes was confirmed. These findings involve highly relevant issues that may open a new range of possibilities in ART.
Reproductive Biology and FertilityReproductive Health and TechnologiesOvarian function and disordersRandomized controlled trialMedicineDonationOocyte donationGynecologyAndrologyOocyteSurgeryBiologyEmbryo
MeSH terms
AdultFemaleHumansInfertility, FemaleOocytesEmbryo ImplantationPregnancyPregnancy OutcomeStatistics as TopicCryopreservationBiological Specimen BanksOocyte DonationPregnancy Rate
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547
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References
Improving cryopreservation systems
Theriogenology · 2005 · 319 citations
Comparison of concomitant outcome achieved with fresh and cryopreserved donor oocytes vitrified by the Cryotop method
Fertility and Sterility · 2007 · 553 citations
Highly efficient vitrification for cryopreservation of human oocytes and embryos: The Cryotop method
Theriogenology · 2006 · 839 citations
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