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Drugs with anticholinergic effects and cognitive impairment, falls and all‐cause mortality in older adults: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology · 2015 · Vol. 80(2) · pp. 209–220
Kimberley RuxtonRichard WoodmanArduino A. Mangoni

Abstract

Certain individual DACEs or increased overall DACE exposure may increase the risks of cognitive impairment, falls and all-cause mortality in older adults.

Pharmaceutical Practices and Patient OutcomesBlood Pressure and Hypertension StudiesIntensive Care Unit Cognitive DisordersMedicineAnticholinergicOdds ratioInternal medicineCochrane LibraryOxybutyninAnticholinergic agentsDrug classRandomized controlled trialPsychiatry

MeSH terms

Accidental FallsAgedAged, 80 and overCognition DisordersFemaleHumansMaleBiasCholinergic Antagonists
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