articleTop 1% cited
Adherence to Medication
New England Journal of Medicine · 2005 · Vol. 353(5) · pp. 487–497
Lars Osterberg✉(VA Palo Alto Health Care System)Terrence F. Blaschke(Stanford University)
Abstract
The full benefit of many effective medications will be achieved only if patients adhere to prescribed treatment regimens. Unfortunately, applying terms such as “noncompliant” and “nonadherent” to patients who do not consume every pill at the desired time can stigmatize them in their future relationships with health care providers. This article on medication adherence (or compliance) reviews strategies to assess and enhance this important aspect of patient care.
Medication Adherence and CompliancePharmaceutical studies and practicesPharmaceutical Practices and Patient OutcomesMedicinePillMedication adherenceIntensive care medicinePatient complianceCompliance (psychology)Health careMEDLINEAlternative medicineFamily medicine
MeSH terms
AdolescentMental DisordersChildChronic DiseaseDrug Administration ScheduleDrug TherapyHumansHypertensionPatient ComplianceHIV Infections
Citations
7,886
FWCI
123.13
field-weighted impact
References
139
Percentile
100%
vs. same field & year
Citations per year
Cited by
Importance of medication adherence for better quality of life in diabetes patients
International Journal of Pharmacognosy and Pharmaceutical Sciences · 2025 · 0 citations
Special Issue: KDIGO Clinical Practice Guideline for the Care of Kidney Transplant Recipients
American Journal of Transplantation · 2009 · 1,421 citations
Medication Adherence Measures: An Overview
BioMed Research International · 2015 · 1,246 citations
EASL Clinical Practice Guidelines: Liver transplantation
Journal of Hepatology · 2015 · 1,037 citations
Adherence to tamoxifen over the five-year course
Breast Cancer Research and Treatment · 2006 · 319 citations
Early discontinuation and non-adherence to adjuvant hormonal therapy are associated with increased mortality in women with breast cancer
Breast Cancer Research and Treatment · 2010 · 872 citations
Physician Communication and Patient Adherence to Treatment
Medical Care · 2009 · 2,395 citations
Medication Adherence: WHO Cares?
Mayo Clinic Proceedings · 2011 · 1,858 citations
References
Interventions for helping patients to follow prescriptions for medications
Cochrane Database of Systematic Reviews · 2002 · 908 citations
Concurrent and Predictive Validity of a Self-reported Measure of Medication Adherence
Medical Care · 1986 · 5,291 citations
The assessment of refill compliance using pharmacy records: Methods, validity, and applications
Journal of Clinical Epidemiology · 1997 · 1,187 citations
Responses to a 1 month self-report on adherence to antiretroviral therapy are consistent with electronic data and virological treatment outcome
AIDS · 2002 · 449 citations
A prospective study of predictors of adherence to combination antiretroviral medication
Journal of General Internal Medicine · 2002 · 517 citations
Compliance With Medication Regimens for Mental and Physical Disorders
Psychiatric Services · 1998 · 734 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.