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Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study

The Lancet · 2004 · Vol. 364(9438) · pp. 937–952

Salim Yusuf✉(Hamilton General Hospital)Steven Hawken(Population Health Research Institute)Stephanie Ôunpuu(Hamilton General Hospital)Tony Dans(Hamilton General Hospital)Álvaro Avezum(Hamilton General Hospital)Fernando Laņas(Population Health Research Institute)Matthew McQueen(Population Health Research Institute)Andrzej Budaj(Hamilton General Hospital)Prem Pais(Population Health Research Institute)George Varigos(Hamilton General Hospital)Lisheng Liu(Population Health Research Institute)

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Abstract

Abnormal lipids, smoking, hypertension, diabetes, abdominal obesity, psychosocial factors, consumption of fruits, vegetables, and alcohol, and regular physical activity account for most of the risk of myocardial infarction worldwide in both sexes and at all ages in all regions. This finding suggests that approaches to prevention can be based on similar principles worldwide and have the potential to prevent most premature cases of myocardial infarction.

Cardiovascular Health and Risk Factors Blood Pressure and Hypertension Studies Diabetes, Cardiovascular Risks, and LipoproteinsMedicineMyocardial infarctionOdds ratioInternal medicineAbdominal obesityDiabetes mellitusPopulationFamily historyDemographyRisk factor

MeSH terms

Alcohol DrinkingApolipoproteinsBody ConstitutionCross-Cultural ComparisonDietFemaleHumansHypertensionMaleMyocardial InfarctionObesityRisk FactorsSmokingSocioeconomic FactorsGlobal Health

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