Label‐Free Colorimetric Detection of Single Nucleotide Polymorphism by Using Single‐Walled Carbon Nanotube Intrinsic Peroxidase‐Like Activity

Abstract

SWNTs possess intrinsic peroxidase-like activity, catalyzing the reaction of peroxidase substrate 3,3,5,5-tetramethylbenzidene (TMB) in the presence of H2O2 to produce a color reaction. Here SWNTs have been used for label-free colorimetric detection of disease-associated single-nucleotide polymorphism with a direct detection limit of 1 nM. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.