review Open AccessTop 10% cited
Mortality and delay in effective therapy associated with extended-spectrum -lactamase production in Enterobacteriaceae bacteraemia: a systematic review and meta-analysis
Journal of Antimicrobial Chemotherapy · 2007 · Vol. 60(5) · pp. 913–920
Mitchell J. Schwaber✉(Tel Aviv Sourasky Medical Center)Yehuda Carmeli(Harvard University)
Abstract
In Enterobacteriaceae bacteraemia, ESBL production is associated with increased mortality and delay in effective therapy. However, lack of controlled studies limits interpretation regarding causality, and further controlled studies are required.
Antibiotic Resistance in BacteriaBacterial Identification and Susceptibility TestingNosocomial Infections in ICUBacteremiaMeta-analysisMedicineOdds ratioRelative riskInternal medicineConfidence intervalConfoundingEnterobacteriaceaeIncidence (geometry)
MeSH terms
Anti-Bacterial Agentsbeta-LactamasesEnterobacteriaceaeEnterobacteriaceae InfectionsHumansBacteremia
Citations
609
FWCI
8.33
field-weighted impact
References
35
Percentile
99%
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Citations per year
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References
Funnel plots for detecting bias in meta-analysis
Journal of Clinical Epidemiology · 2001 · 3,689 citations
The Relationship between Antimicrobial Resistance and Patient Outcomes: Mortality, Length of Hospital Stay, and Health Care Costs
Clinical Infectious Diseases · 2005 · 1,277 citations
Clinical Importance of Delays in the Initiation of Appropriate Antibiotic Treatment for Ventilator-Associated Pneumonia
CHEST Journal · 2002 · 965 citations
Extended-Spectrum β-Lactamases: a Clinical Update
Clinical Microbiology Reviews · 2005 · 3,387 citations
Comparison of Mortality Associated with Methicillin‐Resistant and Methicillin‐Susceptible<i>Staphylococcus aureus</i>Bacteremia: A Meta‐analysis
Clinical Infectious Diseases · 2003 · 1,956 citations
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