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Design, synthesis and biological evaluation of some pyrazole derivatives as anti-inflammatory-antimicrobial agents

Bioorganic & Medicinal Chemistry · 2004 · Vol. 12(8) · pp. 1935–1945
Adnan A. BekhitTarek Abdel-Aziem
Synthesis and biological activityClick Chemistry and ApplicationsSynthesis of heterocyclic compoundsAntimicrobialIn vivoChemistryAnti-inflammatoryStaphylococcus aureusCandida albicansAmpicillinPotencyAntibacterial activityIn vitro

MeSH terms

AnimalsAnti-Infective AgentsAnti-Inflammatory Agents, Non-SteroidalDrug Evaluation, PreclinicalHumansLethal Dose 50MaleMicrobial Sensitivity TestsPyrazolesStomach UlcerDrug DesignRats, Sprague-DawleyMiceRats
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423
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35
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96%
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