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Sequential vs Concurrent Chemoradiation for Stage III Non-Small Cell Lung Cancer: Randomized Phase III Trial RTOG 9410
JNCI Journal of the National Cancer Institute · 2011 · Vol. 103(19) · pp. 1452–1460
Walter J. Curran✉(RTOG Foundation)Rebecca Paulus(National Cancer Center)Corey J. Langer(Henry Ford Hospital)R. Komaki(Emory University)Jong Seok Lee(The University of Texas MD Anderson Cancer Center)Stephen L. Hauser(National Cancer Center)B. Movsas(The University of Texas MD Anderson Cancer Center)Todd H. Wasserman(Intermountain Medical Center)Seth A. Rosenthal(Henry Ford Hospital)Elizabeth Gore(National Cancer Center)Mitchell Machtay(Emory University)William T. Sause(RTOG Foundation)James D. Cox(National Cancer Center)
Abstract
Concurrent delivery of cisplatin-based chemotherapy with TRT confers a long-term survival benefit compared with the sequential delivery of these therapies.
Lung Cancer Diagnosis and TreatmentLung Cancer Treatments and MutationsHepatocellular Carcinoma Treatment and PrognosisMedicineRegimenEtoposideRadiation therapyChemotherapyLung cancerVinblastineClinical endpointChemotherapy regimenCisplatin
MeSH terms
AdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsCanadaCarcinoma, Non-Small-Cell LungCisplatinDrug Administration ScheduleEtoposideFollow-Up StudiesHumansLung NeoplasmsMaleMiddle AgedNeoplasm Staging
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