reviewTop 1% cited
Genomic DNA methylation: the mark and its mediators
Trends in Biochemical Sciences · 2006 · Vol. 31(2) · pp. 89–97
Robert J. Klose(Wellcome Centre for Cell Biology)Adrian Bird✉(Wellcome Centre for Cell Biology)
Epigenetics and DNA MethylationGenetics and Neurodevelopmental DisordersRNA modifications and cancerDNA methylationEpigenetics of physical exerciseEpigeneticsBiologyEpigenomicsChromatinCpG siteHistone methylationGeneticsHistone
MeSH terms
AnimalsDNA (Cytosine-5-)-MethyltransferasesDNA-Binding ProteinsGene Expression RegulationHumansIntestinal NeoplasmsTranscription FactorsTranscription, GeneticRett SyndromeCpG IslandsDNA MethylationGene SilencingEpigenesis, GeneticMethyl-CpG-Binding Protein 2
Funding
- Wellcome Trust
Citations
2,453
FWCI
57.42
field-weighted impact
References
95
Percentile
100%
vs. same field & year
Citations per year
Cited by
On the presence and role of human gene-body DNA methylation
Oncotarget · 2012 · 542 citations
Epigenetics and the Biological Definition of Gene × Environment Interactions
Child Development · 2010 · 1,206 citations
CpG islands and the regulation of transcription
Genes & Development · 2011 · 3,188 citations
Intergenerational Transmission of Stress in Humans
Neuropsychopharmacology · 2015 · 539 citations
Epigenetic mechanisms of drug addiction
Neuropharmacology · 2013 · 444 citations
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
Nature Genetics · 2007 · 2,247 citations
Cell-free nucleic acids as biomarkers in cancer patients
Nature reviews. Cancer · 2011 · 2,859 citations
Epigenetic Transmission of the Impact of Early Stress Across Generations
Biological Psychiatry · 2010 · 1,107 citations
References
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
Nature Genetics · 1998 · 2,718 citations
Suv39h-Mediated Histone H3 Lysine 9 Methylation Directs DNA Methylation to Major Satellite Repeats at Pericentric Heterochromatin
Current Biology · 2003 · 1,224 citations
DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development
Cell · 1999 · 6,039 citations
EUKARYOTIC CYTOSINE METHYLTRANSFERASES
Annual Review of Biochemistry · 2005 · 2,049 citations
Identification and Characterization of a Family of Mammalian Methyl-CpG Binding Proteins
Molecular and Cellular Biology · 1998 · 1,344 citations
Related articles
DNA methylation landscapes: provocative insights from epigenomics
Nature Reviews Genetics · 2008 · 3,047 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.