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Status of myocardial antioxidants in ischemia–reperfusion injury

Cardiovascular Research · 2000 · Vol. 47(3) · pp. 446–456
Naranjan S. Dhalla

Abstract

The available evidence support the role of oxidative stress in ischemia-reperfusion injury and emphasize the importance of antioxidant mechanisms in cardioprotection.

Cardiac Ischemia and ReperfusionAnesthesia and Neurotoxicity ResearchCardiac Arrest and ResuscitationIschemiaMedicineOxidative stressCardioprotectionReperfusion injuryGlutathione peroxidasePharmacologyAntioxidantReactive oxygen speciesSuperoxide dismutase

MeSH terms

AcetylcysteineAnimalsAntioxidantsCatalaseGlutathione PeroxidaseHumansMyocardial ContractionMyocardiumSuperoxide DismutaseVitamin EMyocardial Reperfusion InjuryApoptosisOxidative StressIschemic Preconditioning, Myocardial
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