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Status of myocardial antioxidants in ischemia–reperfusion injury
Cardiovascular Research · 2000 · Vol. 47(3) · pp. 446–456
Naranjan S. Dhalla✉(University of Manitoba)
Abstract
The available evidence support the role of oxidative stress in ischemia-reperfusion injury and emphasize the importance of antioxidant mechanisms in cardioprotection.
Cardiac Ischemia and ReperfusionAnesthesia and Neurotoxicity ResearchCardiac Arrest and ResuscitationIschemiaMedicineOxidative stressCardioprotectionReperfusion injuryGlutathione peroxidasePharmacologyAntioxidantReactive oxygen speciesSuperoxide dismutase
MeSH terms
AcetylcysteineAnimalsAntioxidantsCatalaseGlutathione PeroxidaseHumansMyocardial ContractionMyocardiumSuperoxide DismutaseVitamin EMyocardial Reperfusion InjuryApoptosisOxidative StressIschemic Preconditioning, Myocardial
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References
Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide
Archives of Biochemistry and Biophysics · 1991 · 2,199 citations
Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
Analytical Biochemistry · 1969 · 6,045 citations
The stunned myocardium: prolonged, postischemic ventricular dysfunction.
Circulation · 1982 · 2,801 citations
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