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Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings

Thorax · 2004 · Vol. 59(3) · pp. 252–256
Chung‐Ming Chu

Abstract

The apparent favourable clinical response with lopinavir/ritonavir and ribavirin supports further randomised placebo controlled trials in patients with SARS.

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesRespiratory viral infections researchLopinavirRitonavirMedicineRibavirinAdverse effectLopinavir/ritonavirInternal medicineARDSGastroenterologyImmunology

MeSH terms

AdultAgedCross InfectionDrug Therapy, CombinationFemaleHumansMaleMiddle AgedPyrimidinonesSteroidsOdds RatioTreatment OutcomeHIV Protease InhibitorsDisease ProgressionRitonavir

Funding

  • Queen Mary University of London
  • Wellcome Trust
  • University of Hong Kong
  • Hong Kong Government
  • National Institute of Allergy and Infectious Diseases
Citations
1,698
FWCI
14.86
field-weighted impact
References
24
Percentile
99%
vs. same field & year
Citations per year
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References
Lopinavir/Ritonavir
Drugs · 2003 · 436 citations
The American-European Consensus Conference On Ards. Definitions, Mechanisms, Relevant Outcomes, And Clinical Trial Coordination
American Journal of Respiratory and Critical Care Medicine · 1994 · 6,745 citations
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Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings · Scinovex