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Risk of Mental Illness in Offspring of Parents With Schizophrenia, Bipolar Disorder, and Major Depressive Disorder: A Meta-Analysis of Family High-Risk Studies

Schizophrenia Bulletin · 2013 · Vol. 40(1) · pp. 28–38
D. RasicTomáš HájekMartin AldaRudolf Uher

Abstract

Offspring of parents with SMI are at increased risk for a range of psychiatric disorders and one third of them may develop a SMI by early adulthood.

Maternal Mental Health During Pregnancy and PostpartumChild and Adolescent Psychosocial and Emotional DevelopmentFamily Support in IllnessOffspringBipolar disorderSchizophrenia (object-oriented programming)PsychiatryMental illnessMajor depressive disorderRelative riskBipolar I disorderPsychologyDepression (economics)

MeSH terms

AdolescentAdultBipolar DisorderChildMajor Depressive DisorderDepressive Disorder, MajorFamily RelationsHumansPsychotic DisordersRiskSchizophreniaSeverity of Illness IndexRandomized Controlled Trials as TopicChild of Impaired ParentsGenetic Predisposition to Disease

Funding

  • World Health Organization
Citations
731
FWCI
26.42
field-weighted impact
References
72
Percentile
100%
vs. same field & year
Citations per year
References
The Relative Merits of Risk Ratios and Odds Ratios
Archives of Pediatrics and Adolescent Medicine · 2009 · 483 citations
Journal of Affective Disorders
Journal of Affective Disorders · 1996 · 870 citations
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Risk of Mental Illness in Offspring of Parents With Schizophrenia, Bipolar Disorder, and Major Depressive Disorder: A Meta-Analysis of Family High-Risk Studies · Scinovex