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Macrophages contribute to the initiation of ischaemic acute renal failure in rats

Nephrology Dialysis Transplantation · 2006 · Vol. 21(5) · pp. 1231–1239

Abstract

These results suggest that macrophages are an important mediator in the initiation period of ischaemia/reperfusion injury and strategies that limit initial macrophage infiltration or activation can be useful in the treatment of acute renal failure.

Acute Kidney Injury ResearchNeuroinflammation and Neurodegeneration MechanismsOrgan Transplantation Techniques and OutcomesMedicineMonocyteChemokineCytokineTumor necrosis factor alphaKidneyEndocrinologyInflammationInternal medicineNecrosis

MeSH terms

AnimalsBiopsy, NeedleDisease Models, AnimalImmunohistochemistryInterleukin-1Kidney Function TestsMacrophagesMaleProbabilityReference ValuesRNA, MessengerTumor Necrosis Factor-alphaReperfusion InjuryInterleukin-6Rats, Sprague-Dawley
Citations
324
FWCI
9.68
field-weighted impact
References
18
Percentile
99%
vs. same field & year
Citations per year
Cited by
Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair
Journal of the American Society of Nephrology · 2011 · 884 citations
References
Treatment of acute renal failure
Kidney International · 1998 · 814 citations
Identification and kinetics of leukocytes after severe ischaemia/reperfusion renal injury
Nephrology Dialysis Transplantation · 2000 · 366 citations
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Macrophages contribute to the initiation of ischaemic acute renal failure in rats · Scinovex