articleTop 10% cited
Stability of Endogenous and Added RNA in Blood Specimens, Serum, and Plasma
Clinical Chemistry · 2002 · Vol. 48(10) · pp. 1647–1653
Abstract
Plasma RNA is stable in uncentrifuged EDTA blood stored at 4 degrees C, but to obtain a stable serum RNA concentration, uncentrifuged clotted blood should be stored at 4 degrees C and processed within 6 h. A single freeze/thaw cycle produces no significant effect on the RNA concentration of plasma or serum.
Molecular Biology Techniques and ApplicationsCancer Genomics and DiagnosticsPrenatal Screening and DiagnosticsRNAWhole bloodChemistryBlood plasmaMolecular biologyIncubationRNA extractionMessenger RNAAndrologyBiology
MeSH terms
Blood Specimen CollectionDNADrug StabilityGlobinsGlyceraldehyde-3-Phosphate DehydrogenasesHumansPlasmaRNATime FactorsPolymerase Chain Reaction
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References
Quantitative Analysis of Fetal DNA in Maternal Plasma and Serum: Implications for Noninvasive Prenatal Diagnosis
The American Journal of Human Genetics · 1998 · 1,649 citations
A novel method for real time quantitative RT-PCR.
Genome Research · 1996 · 2,093 citations
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