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Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome

Clinical Endocrinology · 1992 · Vol. 36(1) · pp. 105–111
D. KiddyDiana Hamilton‐FairleyAnne BushFrances ShortV. AnyaokuMichael ReedStephen Franks

Abstract

These data indicate that moderate weight loss during long-term calorie restriction is associated with a marked clinical improvement which reflects the reduction in insulin concentrations and reciprocal changes in SHBG. The improvement in menstrual function and fertility may therefore be consequent upon an increase in insulin sensitivity which, directly or indirectly, affects ovarian function.

Ovarian function and disordersReproductive Biology and FertilityEndometriosis Research and TreatmentPolycystic ovaryInternal medicineEndocrinologyhirsutismMedicineTestosterone (patch)Endocrine systemOvarySex hormone-binding globulinHyperandrogenism

MeSH terms

Body WeightEnergy IntakeFemaleHumansInsulinObesityOvaryPolycystic Ovary SyndromeSex Hormone-Binding GlobulinTestosteroneBody Mass Index

Funding

  • National Institute of Diabetes and Digestive and Kidney Diseases
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Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome · Scinovex